翻訳と辞書 Words near each other ・ Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase ・ Dihydrolipoyllysine-residue succinyltransferase ・ Dihydromethysticin ・ Dihydromorin ・ Dihydromorphine ・ Dihydroneopterin aldolase ・ Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase ・ Dihydroorotase ・ Dihydroorotate dehydrogenase ・ Dihydroorotate dehydrogenase (fumarate) ・ Dihydroorotate dehydrogenase (quinone) ・ Dihydrophloroglucinol ・ Dihydroprogesterone ・ Dihydropteroate ・ Dihydropteroate synthase ・ Dihydropteroate synthase inhibitor ・ Dihydropyran ・ Dihydropyridine ・ Dihydropyrimidinase ・ Dihydropyrimidine dehydrogenase ・ Dihydropyrimidine dehydrogenase (NADP+) ・ Dihydropyrimidine dehydrogenase deficiency ・ Dihydroquinidine ・ Dihydroquinine ・ Dihydrosanguinarine ・ Dihydrosanguinarine 10-monooxygenase ・ Dihydrostilbenoid ・ Dihydrostreptomycin ・ Dihydrostreptomycin-6-phosphate 3'alpha-kinase ・ Dihydrotachysterol Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Dihydropteroate synthase inhibitor ： ウィキペディア英語版 Dihydropteroate synthase inhibitor A dihydropteroate synthase inhibitor is a drug that inhibits the action of dihydropteroate synthase. Most are sulfonamides. In bacteria, antibacterial sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthase, DHPS. DHPS catalyses the conversion of PABA (''para''-aminobenzoate) to dihydropteroate, a key step in folate synthesis. Folate is necessary for the cell to synthesize nucleic acids (nucleic acids are essential building blocks of DNA and RNA), and in its absence cells will be unable to divide. Hence the sulfonamide antibacterials exhibit a bacteriostatic rather than bactericidal effect. ==Uses== Folate is not synthesized in mammalian cells, but is instead a dietary requirement. This explains the selective toxicity to bacterial cells of these drugs. These antibiotics are used to treat pneumocystis jiroveci pneumonia, urinary tract infections, and shigellosis. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dihydropteroate synthase inhibitor」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.